美國Pria醫(yī)學(xué)診斷公司(Menlo Park, CA, USA)與Vanderbilt大學(xué)(Nashville, TN, USA)宣布進(jìn)行生物武器檢查與新出現(xiàn)疾病檢查領(lǐng)域的合作。

公司計(jì)劃聯(lián)合使用Pria公司的微型熒光檢測(cè)儀與Vanderbilt大學(xué)的掌上診斷系統(tǒng)，來研制能夠快速檢測(cè)免疫熒光抗原的一體化產(chǎn)品。他們打算使用聯(lián)合檢測(cè)工藝，在移動(dòng)生物武器和新出現(xiàn)疾病的檢測(cè)領(lǐng)域，得到與在實(shí)驗(yàn)室進(jìn)行檢測(cè)的水平。

Pria公司的微型熒光檢測(cè)儀包含固態(tài)元件、多聚體光學(xué)器件、整合數(shù)字控制系統(tǒng)，可以替代目前使用的熒光檢測(cè)的復(fù)雜機(jī)械設(shè)備。新儀器便攜、輕巧、功能強(qiáng)大，而且能夠低成本大批量生產(chǎn)。微型熒光檢測(cè)儀具有熒光檢測(cè)領(lǐng)域所必須的敏感性和準(zhǔn)確性，可以廣泛應(yīng)用于篩查化學(xué)武器、生物武器、慢性傳染性疾病以及有害的環(huán)境。

“Vanderbile大學(xué)在生物微電子機(jī)械系統(tǒng)領(lǐng)域具有世界級(jí)研究水平，”Pria公司首席科技官員Jason Pyle博士說，“將他們的技術(shù)與我們的平臺(tái)進(jìn)行整合，預(yù)示著以前只能在實(shí)驗(yàn)室進(jìn)行的熒光檢測(cè)方法將具有更多的靈活性。”美迪醫(yī)療網(wǎng)成揚(yáng)報(bào)道。

Companies to Collaborate on Bioweapons Detection
 
A collaboration focused on bioweapons and emerging-disease detection has been announced by Pria Diagnostics (Menlo Park, CA, USA) and Vanderbilt University (Nashville, TN, USA).

The companies plan to combine Pria’s miniaturized fluorescence reader with Vanderbilt’s lab-on-a-chip diagnostic assays to develop products that can rapidly detect immunofluorescent antigens in a handheld package. They intend to use the combined technologies to produce laboratory-quality infectious disease testing, initially for applications in the detection of mobile bioweapons and emerging diseases.

Pria’s microfluorimeter combines solid-state component, polymer optics, and an integrated digital control system to replace the complex machinery used in current fluorescent detectors. As a result, the platform is portable, lightweight, and mechanically robust in a device that can be manufactured at low cost in high volume. The microfluorimeter has the sensitivity and fidelity required in a wide range of fluorescent assays, including the screening for chemical and biologic weapons, chronic and infectious diseases, and hazardous environmental conditions.

“Vanderbilt has clearly differentiated itself as a world class research facility in the area of biological MEMS (microelectromechanical systems),” noted Jason Pyle, Ph.D., chief scientific officer for Pria. “The integration of their technology with our platform shows how fluorescence testing achieves diagnostic capabilities previously only available through a laboratory.”