一種新型設備被設計用于防止充血性心衰患者在接受冠狀動脈手術的時候出現腎功能不全。

慢性腎臟疾病合并充血性心衰會增加由于血管造影術中使用的染料或者支架手術時候發生腎臟功能衰竭的危險。這套Benephit Delta系統是以導管為基礎的醫療設備，能夠將特定藥物和其它治療藥物直接輸送到腎動脈。系統能夠對兩根腎動脈同時進行選擇性給藥，而只需使用一根導管。設計這套系統的主要目的是進行靶向腎臟治療，作為系統性靜脈注射藥物治療充血性心衰相關腎臟功能不全的替代選擇。

近期在美國NewYork-Presbyterian醫院一例男性患者中進行了這種操作程序，該患者當時接受血管擴張手術以治療冠狀動脈重度阻塞。在他的冠狀動脈中放置了5個支架，這需要使用大劑量的染料。手術中使用Benephit Delta系統將一種藥物 (非諾多泮)通過腎臟動脈直接輸送到患者的腎臟，以增加血流量。患者沒有出現危及生命的放射造影劑腎病。心血管醫生估計大約有20％接受冠狀動脈干預手術的患者能夠從對放射造影劑腎病的治療中獲益。

Benefit Delta系統是由美國FlowMedica公司研制開發的，這是一家醫療設備公司。

Device Helps Prevent Kidney Dysfunction
 
A new device is designed to help prevent kidney dysfunction in patients with congestive heart failure (CHF) while undergoing coronary procedures.

The combination of chronic kidney disease and CHF greatly increases a patient’s risk of developing kidney failure from the dye used during an angiography or stenting procedure. The Benephit Delta system is a catheter-based medical device that enables the administration of specified medications and other therapeutic agents directly to the renal arteries. The system can provide selective infusion to both renal arteries simultaneously, using a single catheter. It is designed to provide targeted renal therapy (TRT), an alternative to systemic intravenous infusion of medications to treat kidney dysfunction related to CHF.

The procedure was recently used on a male patient at NewYork-Presbyterian Hospital (NY, USA) who had recently had angioplasty to treat two severely blocked coronary arteries. Five stents were placed in his coronary arteries, which required large amounts of dye. The Benephit Delta system was used to deliver a medication (fenoldopam) directly into the patient’s kidneys through the renal arteries to increase blood flow. The patient did not develop the potentially life-threatening condition known as radiocontrast nephropathy (RCN). Cardiologists estimate that about 20% of patients undergoing coronary interventions could benefit from treatment for RCN.

The Benefit Delta system was developed by FlowMedica, a medical device company (Fremont, CA, USA).