一種便攜式電池供電的吸入設(shè)備，被設(shè)計(jì)用于治療肺動(dòng)脈性高血壓。

CoTherix公司(San Francisco, CA, USA)和Respironics公司(Murrysville, PA, USA)已經(jīng)宣布將I-neb自適應(yīng)性氣溶膠輸送(AAD)設(shè)備用于Ventavis吸入解決方案。

I-neb只有不到8盎司中，能夠被放置于錢包、口袋或者公文箱中，配合Respironics的AAD系統(tǒng)使用，能夠持續(xù)適應(yīng)患者個(gè)體呼吸模式來發(fā)揮作用，只需要吸氣就可以完成給藥。

Ventavis適合用于治療出現(xiàn)III級(jí)或者IV級(jí)癥狀的肺動(dòng)脈性高血壓(PAH)患者。Ventavis是iloprost的吸入劑型，是一種合成化合物，結(jié)構(gòu)上類似于環(huán)前列腺素，環(huán)前列腺素是自然生成的分子，能夠?qū)е卵苁鎻垺Ｃ绹?guó)食品與藥品管理局在2005年8月擴(kuò)大了CoTherix的標(biāo)簽，允許使用I-neb作為Ventavis的給藥方法。

肺動(dòng)脈性高血壓是一種罕見的肺部血管疾病，肺動(dòng)脈壓力高出正常水平，患者有生命危險(xiǎn)。該疾病的病因目前尚不清楚，但是肺部血流受限制的疾病包括硬皮病、艾滋病和紅斑狼瘡都會(huì)導(dǎo)致該病的發(fā)生。

該病癥狀包括乏力、呼吸短促、胸痛和眩暈。如果不治療，明確診斷之后的中位數(shù)生存時(shí)間不到3年。但是經(jīng)過治療部分患者能夠控制該病，達(dá)15～20年之久，甚至更長(zhǎng)。

Device for Pulmonary Hypertension
 
A portable, battery-operated inhalation device is designed for the treatment of pulmonary arterial hypertension.

CoTherix (San Francisco, CA, USA) and Respironics, (Murrysville, PA, USA) have announced the launch of the I-neb adaptive aerosol delivery (AAD) device for Ventavis inhalation solution.

The I-neb weighs less than eight ounces and can be carried discreetly in a purse, pocket, or briefcase and employs Respironics’ AAD System, which continually adapts to an individual patient’s breathing pattern and delivers medication only on inspiration.

Ventavis is indicated for the treatment of pulmonary arterial hypertension (PAH) in patients with Class III or IV symptoms. Ventavis is an inhaled formulation of iloprost, a synthetic compound that is structurally similar to prostacyclins, naturally occurring molecules that cause blood vessels to dilate. The U.S. Food and Dug Administration (FDA) expanded CoTherix’s label in August 2005 to include the use of the I-neb for the administration of Ventavis.

Pulmonary hypertension is a rare blood vessel disorder of the lungs in which the pressure in the pulmonary artery rises above normal levels and may become life threatening. Its cause is currently unknown, but may result from other diseases that cause a restriction of blood flow to the lungs, including scleroderma, HIV and lupus.

Symptoms of the disease include fatigue, shortness of breath upon exertion, chest pain, and dizziness. Left untreated, the median survival time following diagnosis may be as short as three years. However, under treatment some patients are able to manage the disorder for 15 to 20 years or longer.