首頁 > 美迪醫訊 > 飲食和鍛煉是提高乳腺癌生存率的關鍵,無論病人是否肥胖 |
飲食和鍛煉是提高乳腺癌生存率的關鍵,無論病人是否肥胖 【?2007-06-14 發布?】 美迪醫訊
乳腺癌患者健康飲食加上中度鍛煉可以減輕該病的死亡率達一半以上,而與病人的體重無關,以上的結論是由美國加州Moores腫瘤研究中心最新的一項研究表明的。 先前已有研究觀察飲食和體育鍛煉對乳腺癌患者的影響,得到的結果是相互獨立的。本次研究,刊登于臨床腫瘤學雜志6月10日號,是第一次針對飲食和體育鍛煉對乳腺癌的聯合效應所做的調查。 “本研究所針對的研究對象,無論其胖瘦,如果她每天至少吃五次蔬菜和水果并且精力充沛地完成30分鐘的步行,每周6天的話,那么這些病人因乳腺癌死亡的概率將下降50%。”本研究的第一作者John Pierce博士說。他是Moores腫瘤中心腫瘤預防和控制項目的負責人。他還強調:“關鍵是要兩者同時做。” 該研究回顧了1,490名70歲或以下的早期階段的乳腺癌患者,這些病人是婦女健康飲食和生活研究(WHEL)的研究對象。WHEL是多-機構合作的研究項目,調查基于植物性的飲食是否會對乳腺癌產生其他影響。 研究中所涉及的女性在1991年到2000年之間被診斷患有早期乳腺癌。并且在研究登記前已進行了初次治療。登記時對其飲食和體育鍛煉模式做了記錄。這些病人隨訪了5到11年。 研究人員發現僅有16%的肥胖婦女平時進行體育鍛煉并且具有健康的飲食。同時進行鍛煉和健康飲食的病人比剩余研究對象的生存率要高得多。其死亡率僅為7%,約為其他病人的一半。 “值得一提的是,死亡風險降低一半的效應同時見于非肥胖和肥胖病人,”本研究的其他作者Cheryl Rock博士說,“而這種效應并不見于只有上述生活方式之一的病人---高蔬菜和水果攝取量,或體育鍛煉。” 來源:http://www.newswise.com/articles/view/530610/ University of California, San Diego Diet and Exercise Key to Surviving Breast Cancer, Regardless of Obesity Newswise — Breast cancer survivors who eat a healthy diet and exercise moderately can reduce their risk of dying from breast cancer by half, regardless of their weight, suggests a new longitudinal study from the Moores Cancer Center at the University of California, San Diego (UCSD). Previous studies have looked at the impact of diet or physical activity on breast cancer survival, with mixed results. This study, published in the June 10 issue of the Journal of Clinical Oncology, is the first to look at a combination of both in breast cancer. “We demonstrate in this study of breast cancer survivors that even if a woman is overweight, if she eats at least five servings of vegetables and fruits a day and walks briskly for 30 minutes, six days a week, her risk of death from her disease goes down by 50 percent,” said the paper’s first author, John Pierce, Ph.D., director of the Cancer Prevention and Control Program at the Moores UCSD Cancer Center. “The key is that you must do both.” The study looked at 1,490 women aged 70 years and younger (average 50 years) with early stage breast cancer who were randomly assigned to the non-intensive dietary arm of the ongoing Women’s Health Eating and Living (WHEL) study. The study is a multi-center study, based at UCSD, investigating the effect of a plant-based diet on additional breast cancer events. The women in the study were diagnosed with early stage breast cancer between 1991 and 2000 and had completed their primary therapy prior to enrollment. Dietary pattern and physical activity were assessed at enrollment and the women were followed for between five and 11 years. The researchers found that only 16 percent of women who were obese were both physically active and had a healthy diet, compared to 30 percent in the rest of the study population. Those who were both physically active and had a healthy diet were much more likely to survive through the follow-up period than the rest of the study group. The mortality rate was 7 percent, approximately half of that seen for the rest of the study population. “Of particular importance is that this halving of risk was seen in women who were not obese as well as in those who were obese,” said co-author Cheryl Rock, Ph.D., R.D., of the Center’s Cancer Prevention and Control Program. “Also, the effect was not seen in women who practiced only one of the lifestyle patterns – high vegetable and fruit intake, or physical activity.” Because of the strength of the findings from this longitudinal (observational) study, the researchers want to further investigate the combined protective effect of diet and physical activity on breast cancer survival in an interventional study in which they will change the diet and level of physical activity in breast cancer survivors.Besides Pierce and Rock, who are both faculty members of the Department of Family and Preventive Medicine at the UCSD School of Medicine, co-authors are: Marcia L. Stefanick, Stanford Prevention Research Center, Stanford University, Palo Alto, CA; Shirley W. Flatt, Loki Natarajan, Lisa Madlensky, Wael K. Al-Delaimy, Sheila Kealey, Barbara A. Parker, and Vicky A. Newman, Moores Cancer Center, University of California, San Diego; Barbara Sternfeld, Division of Research, Kaiser Permanente Northern California, Oakland, California; Cynthia A. Thompson, Arizona Cancer Center, University of Arizona, Tucson;&n 本文關鍵字:
提高乳腺癌生存率
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