與流行的醫(yī)學(xué)觀點(diǎn)相反，癲癇手術(shù)數(shù)周后的癲癇發(fā)作提示該患者將會有癲癇持續(xù)發(fā)作。

澳大利亞墨爾本大學(xué)研究人員進(jìn)行的一項(xiàng)研究發(fā)現(xiàn)了這些結(jié)果，該研究涵蓋了接受顳葉切除術(shù)治療癲癇的325例患者。這是一種最普通的治療癲癇的手術(shù)。該區(qū)域是癲癇的始發(fā)區(qū)域，大多數(shù)患者可以去除或者減少癲癇發(fā)作。

墨爾本大學(xué)Anne M.McIntosh博士說：“我們推測某些接受這種手術(shù)的患者仍然出現(xiàn)癲癇發(fā)作的原因更加頑固?！?BR>McIntosh博士和同事發(fā)現(xiàn)這些患者在術(shù)后4周開始有癲癇發(fā)作，而沒有手術(shù)相關(guān)的激發(fā)原因諸如創(chuàng)傷或者腫脹，這些患者在數(shù)月后出現(xiàn)持續(xù)癲癇發(fā)作的可能性增高了8倍。研究人員指出：許多出現(xiàn)癲癇復(fù)發(fā)的患者并沒有從手術(shù)獲得發(fā)作頻率下降的益處。這些研究結(jié)果報(bào)道在2005年1月24日的《神經(jīng)病學(xué)年報(bào)》。
 
Seizures After Epilepsy Surgery
 
Contrary to the prevailing medical understanding, seizures in the weeks following epilepsy surgery signal a greatly increased likelihood that the patient will continue to have seizures.

These findings were the result of a study conducted by researchers at the University of Melbourne (Australia) involving 325 patients who underwent temporal lobe removal (lobectomy) for treatment of epilepsy. This is the most common form of epilepsy surgery. It is in the area where seizures commonly begin and eliminates or reduces seizures in most cases.

“We can speculate that some individuals who undergo this procedure have epilepsy that for some reason is more persistent,” commented lead author Anne M. McIntosh, Ph.D., of the University of Melbourne.

Dr. McIntosh and colleagues found that patients who experienced a seizure in the four weeks following surgery--in the absence of surgery-related triggers such as trauma or swelling-- were eight times more likely to have persistent epilepsy several months later. Still, the researchers noted that many of the patients who have epilepsy recur do have the benefit of reduced seizure frequency. The results were reported in the January 24, 2005, issue of the Annals of Neurology.