來自臨床試驗(yàn)的結(jié)果證實(shí)：患者對使用Enteryx方案減輕胃食管返流疾病（GERD）癥狀的效果感到很滿意。

Enteryx是一種門診手術(shù)，一個小時之內(nèi)即可完成。醫(yī)生將柔軟的內(nèi)窺鏡插入患者嘴巴和食管。內(nèi)窺鏡幫助醫(yī)生觀察患者食管和胃的內(nèi)壁。將一個小針插入內(nèi)窺鏡的工作管腔，用于注射Enteryx溶液，這是一種共聚物，海綿樣物質(zhì)，設(shè)計用于幫助下段食管括約肌（LES）在胃和食管之間形成更有效的屏障，從而減輕GERD的癥狀。Enteryx是波士頓科學(xué)集團(tuán)的產(chǎn)品。

印地安那州大學(xué)醫(yī)學(xué)中心醫(yī)學(xué)系、醫(yī)學(xué)和放射學(xué)教授Glen Lehman醫(yī)生觀察說：“這些臨床試驗(yàn)的結(jié)果證實(shí)了Enteryx方案在控制GERD癥狀方面的安全性和效能，與每日使用質(zhì)子泵抑制劑相比較，Enteryx方案能夠使患者產(chǎn)生最高水平的滿意度。”

這些臨床試驗(yàn)結(jié)果在2005年5月芝加哥舉行的年度消化疾病周會議上做了報道。在臨床試驗(yàn)中，問卷調(diào)查表顯示：接受Enteryx方案的患者反映GERD癥狀得到了確實(shí)的緩解，能夠自由的進(jìn)食和飲水，睡眠得到改善，總體治療滿意程度很高。
 
Studies Support Use of Enteryx for GERD
 
The results of four clinical trials have demonstrated patient satisfaction and the effectiveness of the Enteryx procedure in relieving the symptoms of gastroesophageal reflux disease (GERD).

Enteryx is an outpatient procedure that usually takes less than an hour to complete. A doctor passes a long flexible tube called an endoscope through a patient’s mouth and into the esophagus. The endoscope lets the doctor see the lining of the patient’s esophagus and stomach. A small needle, inserted through the working channel of the endoscope, is used to inject the Enteryx solution, a copolymer, into the muscle layer of the esophagus. Once injected, the Enteryx solution forms a soft, sponge-like material designed to help the lower esophageal sphincter (LES) form a more effective barrier between the stomach and the esophagus, reducing the symptoms of GERD. Enteryx is the product of Boston Scientific Corp. (Natick, MA, USA).

“These clinical trial results demonstrate the safety and efficacy of the Enteryx procedure at controlling GERD symptoms, and show that the Enteryx procedure contributes to high levels of patient satisfaction as compared to daily proton pump inhibitor (PPI) treatments,” observed Glen Lehman, M.D., professor of medicine and radiology, department of medicine, Indiana University Medical Center (Bloomington, IN, USA; www.indiana.edu/medical).

The trial results were presented at the annual Digestive Disease Week conference in Chicago (IL, USA) in May 2005. In one trial, a questionnaire revealed that patients who had the Enteryx procedure reported substantial improvement in GERD symptom control, freedom to eat and drink, ability to sleep better, and overall higher rates of treatment satisfaction.