一種改良規(guī)劃設(shè)計(jì)被開發(fā)用于MicroScan干燥革蘭氏陽(yáng)性過(guò)夜抗微生物易感性檢測(cè)面板。這種新的改良規(guī)劃設(shè)計(jì)已經(jīng)獲得了美國(guó)食品藥品管理局的許可。

由于金黃色葡萄球菌耐藥性不斷增加，Dade Behring現(xiàn)在供應(yīng)的這種自動(dòng)化系統(tǒng)改進(jìn)了對(duì)耐萬(wàn)古霉素金黃色葡萄球菌的檢測(cè)。

Dade Behring公司MicroScan臨床與科學(xué)事務(wù)部主任Barbara Zimmer博士解釋說(shuō)：“我們的研究團(tuán)隊(duì)知道這對(duì)臨床醫(yī)生和他們的患者而言是多么的重要；我們了解萬(wàn)古霉素是一個(gè)十分重要的抗菌藥，在治療耐甲氧西林和其他抗生素的金黃色葡萄球菌方面發(fā)揮著重要作用。”

根據(jù)美國(guó)疾病控制與預(yù)防中心(Atlanta, GA, USA; www.cdc.gov)的資料，需要使用最小抑制濃度(MIC)來(lái)檢測(cè)金黃色葡萄球菌對(duì)萬(wàn)古霉素的耐藥性。所有Dade Behring公司的MicroScan檢測(cè)面板都是以MIC方法為基礎(chǔ)，被認(rèn)為在確定抗微生物藥物對(duì)抗菌藥物的易感性方面是最敏感的方法。迄今為止，已經(jīng)報(bào)道了四種耐萬(wàn)古霉素的金黃色葡萄球菌菌株。根據(jù)該公司MicroScan自動(dòng)檢測(cè)系統(tǒng)的精確性，Dade Behring一直致力于檢測(cè)這些菌株。
 
Antimycrobial Susceptibility Testing
 
An improved formulation has been developed for MicroScan dried Gram-positive overnight antimicrobial susceptibility test panels. The new formulation has been cleared by the U.S. Food and Drug Administration (FDA).

Dade Behring (Deerfield, IL, USA) is now offering this automated system for the improved detection of vancomycin-resistant Staphylococcus aureus (VRSA) because of the increasing resistance of S aureus strains.

“Our research team knows how critical this issue is to clinicians and their patients; we understand that vancomycin continues to be a critical antimicrobial agent for treating infections caused by S aureus strains that are resistant to the penicillins and other microbial agents,” explained Barbara Zimmer, Ph.D., director of clinical and scientific affairs, Dade Behring, MicroScan.

According to the U.S. Centers for Disease Control and Prevention (Atlanta, GA, USA; www.cdc.gov), S aureus should be tested for resistance to vancomycin using a minimal inhibitory concentration (MIC) method. All of Dade Behring’s MicroScan testing panels are based on the MIC method, which is considered to be the most sensitive method to determine susceptibility to antimicrobial agents. To date, four strains of vancomycin-resistant S aureus have been reported. Dade Behring has continued to detect these strains due to the accuracy of the company’s MicroScan automated system.